Young, J.J.*, Mehdi, A.*, Stohl, L., Levin, L.R., Buck, J., Wagner, J.A., and Stessin, A.M. (2007). 'Soluble' adenylyl cyclase-generated cyclic AMP promotes fast migration in PC12 cells. J. Neurosci. Res. 86: 118-124.
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Schmid, A., Sutto, Z., Nlend, M., Horvath, G., Schmid, N., Buck, J., Levin, L.R., Conner, G., Fregien, N., and Salathe, M. (2007). Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP. J. Gen. Phys. 130: 99-109.
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Beltran, C., Vacquier, V.D., Moy, G., Chen, Y., Buck, J., Levin, L.R., and Darszon, A. (2007). Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction. BBRC358: 1128-1135.
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Wu, K.Y., Zippin, J.H., Huron, D.R., Kamenetsky, M., Hengst, U., Buck, J., Levin, L.R., and Jaffrey, S.R. (2006). Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nature Neuroscience.9: 1257-1264.
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Kamenetsky, M., Middelhaufe, S. Bank, E.M., Levin, L.R., Buck, J., and Steegborn, C. (2006). Molecular details of cAMP generation in mammalian cells: A tale of two systems. J. Mol. Biol.362: 623-629.
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Stessin, A.M., Zippin, J.H., Kamenetsky, M., Hess, K.C., Buck, J., and Levin, L.R. (2006). Soluble adenylyl cyclase mediates NGF-induced activation of RAP1. J. Biol. Chem. 281: 17253-17258.
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Mogensen, E.G., Janbon, G., Chaloupka, J., Steegborn, C., Fu, M.S., Moyrand, F., Klengel, T., Pearson, D.S., Geeves, M.A., Buck, J., Levin, L.R. and Muhlschlegel, F.A. (2006). Cryptococcus senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryotic Cell5:103-111.
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Chaloupka, J.A., Bullock, S.A., Iourgenko, V., Levin, L.R., and Buck, J. (2006). Autoinhibitory regulation of soluble adenylyl cyclase. Mol. Repro. & Dev.73: 361-368.
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Klengel, T.*, Liang, W-J.*, Chaloupka, J.A.*, Ruoff, C., Schroppel, K., Naglik, J.R., Eckert, S.E., Gewiss, E., Haynes, K., Tuitte, M.F., Levin, L.R., Buck, J., and Muhlschlegel, F.A. (2005). Fungal adenylyl cyclase integrates CO2 sensing with cAMP signalling and virulence. Curr. Biol.15: 2021-2026.
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Steegborn, C.*, Litvin, T.N.*, Hess, K.C., Capper, A.B., Taussig, R., Buck, J., Levin, L.R., and Wu, H. (2005). A novel mechanism for adenylyl cyclases inhibition from the crystal structure of its complex with catechol estrogen. J. Biol. Chem. 280:31754-9.
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Hess, K.C.*, Jones, B.H.*, Marquez, B., Chen, Y., Ord, T.S., Kamenetsky, M., Myamoto, C., Zippin, J.H., Kopf, G.S., Suarez, S.S., Levin, L.R.*, Williams, C.J.*, Buck, J.*, and Moss, S.B.* (2005). 'Soluble' Adenylyl Cyclase mediates Multiple Specific Signaling Events in Sperm Required for Fertilization. Dev. Cell 9: 249-259.
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Han, H., Stessin, A.M., Roberts, J., Hess, K.C., Gautam, N., Kamenetsky, M., Lou, O., Hyde, E., Nathan, N., Muller, W.A., Buck, J., Levin, L.R., and Nathan, C. (2005). Role of Calcium-Sensing Soluble Adenylyl Cyclase in TNF Signal Transduction in Human Neutrophils. J. Exp. Med. 202: 353-361.
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Steegborn, C., Litvin, T.N., Levin, L.R., Buck, J., and Wu, H. (2005). Bicarbonate activation of adenylyl cyclase via promotion of the catalytic cycle: active site closure and metal recruitment. Nature Str. & Mol. Biol. 12:32-37.
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Kobayashi, M., Buck, J., and Levin, L.R. (2004). Conservation of functional domain structure in bicarbonate-regulated 'soluble' adenylyl cyclases in bacteria and eukaryotes. Dev. Genes & Evol. 214:503-509.
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Zippin, J.H., Farrell, J., Huron, D., Kamenetsky, M., Hess, K.C., Fischman, D.A., Levin, L.R., and Buck, J. (2004). Bicarbonate responsive 'soluble' adenylyl cyclase defines a nuclear cAMP microdomain. J. Cell. Biol. 164:527-534.
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Pastor-Soler, N., Beaulieu, V., Litvin, T.N., Da Silva, N., Chen, Y., Brown, D., Buck, J., Levin, L.R., and Breton, S. (2003). Bicarbonate regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling. J. Biol. Chem. 278:49523-49529.
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Litvin, T.N., Kamenetsky, M., Zarifyan, A., Buck, J., and Levin, L.R. (2003). Kinetic Properties of 'soluble' adenylyl cyclase: synergism between calcium and bicarbonate. J. Biol. Chem. 278:15922-15926.
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Sun, X.C., Zhai, C.-B., Miao, C., Chen, Y., Levin, L.R., Buck, J., and Bonanno, J.A. (2003). HCO3-dependent soluble adenylyl cyclase activates the cystic fibrosis transmembrane conductance regulator in corneal endothelium. Amer. J. of Physiol. 284:C1114-1122.
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Zippin, J.H.*, Chen, Y.*, Nahirney, P.*, Kamenetsky, M., Wuttke, M.S., Fischman, D.A., Levin, L.R. and Buck, J. (2003). Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains. FASEB Journal 17: 82-84.
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Buck, J., Sinclair, M.L., and Levin, L.R. (2002). Purification of Soluble adenylyl cyclase. Methods in Enzymology 345:95-105.
Zippin, J.H., Levin, L.R., and Buck, J. (2001). Bicarbonate/CO2 responsive soluble adenylyl cyclase as a putative metabolic sensor. Trends in Endocrinology & Metabolism12: 366-370.
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Wuttke, M.S., Buck, J., and Levin, L.R. (2001). Bicarbonate regulated soluble adenylyl cyclase. Journal of the Pancreas 2:154-158.
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Chen, Y.*, Cann, M.J.*, Litvin, T.N., Iourgenko, V., Sinclair, M.L., Levin, L.R., and Buck, J. (2000). Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science 289: 625-628.
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Sinclair, M.L., Wang, X.-Y., Mattia, M., Conti, M., Buck, J., Wolgemuth, D.J., and Levin, L.R. (2000). Specific expression of soluble adenylyl cyclase in male germ cells. Mol. Repro. & Dev.56:6-11.
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Buck, J.*, Sinclair, M.L.*, Schapal, L. Cann, M.J., and Levin, L.R. (1999). Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals. Proc. Natl. Acad. Sci. 96: 79-84.
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Levin, L.R. and Reed, R.R. (1995). Identification of functional domains of adenylyl cyclase using in vivo chimeras.J. Biol. Chem. 270: 7573-7579.
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Cann, M.J. and Levin, L.R. (1998). Genetic characterization of adenylyl cyclase function. In Advances in Second Messenger and Phosphoprotein Research: (32) Adenylyl Cyclases, D.M.F. Cooper, ed. (New York: Raven Press), pp 121-135.
Iourgenko, V., Kliot, B., Cann, M.J., and Levin, L.R. (1997). Cloning and Characterization of a Drosophila adenylyl cyclase homologous to mammalian Type IX. FEBS Letters413:104-108. (FEBS abstract)
Levin, L.R., Han, P.-L., Hwang, P.M., Feinstein, P.G., Davis, R.L., and Reed, R.R. (1992). The Drosophila learning and memory gene, rutabaga, encodes a Ca2+/Calmodulin-responsive adenylyl cyclase. Cell68: 479-489. (Cell Summary)
Han, P.-L., Levin, L.R., Reed, R.R., and Davis, R.L. (1992). Preferential expression of the Drosophilarutabaga gene in mushroom bodies, neural centers for learning in insects. Neuron9: 619-627. (Neuron Summary)
Pakhomova S, Kobayashi M, Buck J, Newcomer ME. (2001).
A helical lid converts a sulfotransferase to a dehydratase.
Nat Struct Biol.8(5):447-51.
Pakhomova S, Luz JG, Kobayashi M, Mellman D, Buck J, Newcomer ME. (2000).
Crystallization of retinol dehydratase from Spodoptera frugiperda: improvement of crystal quality by modification by ethylmercurythiosalicylate.
Acta Crystallogr D Biol Crystallogr. 56 Pt 12:1641-3.
Chen Y, Buck J. (2000). Cannabinoids protect cells from oxidative cell death: a receptor-independent mechanism.
J Pharmacol Exp Ther.293(3):807-12.
Vakiani, E., Luz, J.G., and Buck, J. (1998). Substrate specificity and kinetic mechanism of the insect sulfotransferase, retinol dehydratase. J. Biol. Chem. 273:35381-35387. (JBC Full-text - subscription required)
Chen, Y., Derguini, F., and Buck, J. (1997). Vitamin A in serum is a survival factor for fibroblasts. Proc Natl Acad Sci U S A. 94:10205-8.
(PNAS Full-text)
O'Connell, M.J., Chua, R., Hoyos, B., Buck, J., Chen, Y., Derguini, F., Hammerling, U. (1996). Retro-retinoids in regulated cell growth and death. J. Exp. Med.184:549-55.
(PUBMED abstract)
