Receptive Field Analysis

The use of m-sequences in the analysis of visual neurons: Linear receptive field properties

R. C. Reid, Jonathan D. Victor, and Robert M. Shapley

Visual Neuroscience 14, 1015-1027 (1997)

Abstract

We have used Sutter's (1987) spatiotemporal m-sequence method to map the receptive fields of neurons in the visual system of the cat. The stimulus consisted of a grid of 16 by 16 square regions, each of which was modulated in time by a pseudorandom binary signal, known as an m-sequence. Several strategies for displaying the m-sequence stimulus are presented. The results of the method are illustrated with two examples. For both geniculate neurons and cortical simple cells, the measurement of first-order response properties with the m-sequence method provided a detailed characterization of classical receptive field structures. First, we measured a spatiotemporal map of both the center and surround of a Y-cell in the lateral geniculate nucleus (LGN). The time-courses of the center responses was biphasic: off at short latencies, on at longer latencies. The surround was also biphasic-- on then off-- but somewhat slower. Second, we mapped the response properties of an area 17 directional simple cell. The response dynamics of the on and off subregions varied considerably; the time to peak ranged over more than a factor of two. This spatiotemporal inseparability is related to the cell's directional selectivity (Reid et al., 1987, 1991; McLean et al., 1989, 1994). The detail with which the time-course of response can be measured at many different positions is one of the strengths of the m-sequence method.


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Background on m-sequences
An extension of the m-sequence method
Dynamics of bipolar cells explored with m-sequences
Publications related to receptive field analysis
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