Recovery of consciousness after severe brain injury:
Arousal regulation and heart-brain interface
Recovery of consciousness after severe brain injury:
The role of arousal regulation mechanisms and
some speculation on the heart-brain interface
Nicholas D. Schiff
Cleveland Clinic Journal of Medicine 77 Suppl 3, S27-33 (2010)
Abstract
Recovery of consciousness after severe brain injury
involves reconstitution of brain arousal mechanisms and
cerebral integrative function. This review discusses several
aspects of neuroanatomy and neuropathology relevant to
the process of recovery. Particular emphasis is placed on
the role of the anterior forebrain and circuit mechanisms
linking the frontal lobe, striatum, and central thalamus.
The article concludes with some observations on the
heart-brain interface and future research directions in
the context of recovery from severe brain injury.
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