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T.A. Ryan Bibliography

 

red button 2008
1
    J. Balaji & T. A. Ryan. Caclium control of endocytic capacity at a CNS synapse. J. Neuroscience (2008) 28, 6742-6749.

2007
1
    J. Balaji & T. A. Ryan. Single vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode. Proc. Nat. Acad. Sci (2007) 104, 20576-8.
2
    M . Mani, S-Y Lee, L. Lucast, O. Cremona, G. Di Paolo, P. De Camilli, T. A. Ryan. The dual phosphatase activity of Synaptojanin1 is required for both efficient synaptic vesicle internalization and re-availability at nerve terminals. Neuron (2007) 56, 1004-18.
3
    L-G. Wu, T. A. Ryan, L. Lagnado. Modes of Vesicle Retrieval at Ribbon Synapses, Calyx-Type Synapses, and Small Central Synapses. J. Neuroscience (2007) 27,11793-802.
4

S. M. Ferguson , G. Brasnjo, M. Hayashi, M. Wolfel , C. Collesi, S. Giovedi, A. Raimondi, L. W. Gong , P. Ariel P, S. Paradise, E. O'toole, R. Flavell, O. Cremona , G. Miesenbock ,T. A. Ryan, P. De Camilli. A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science (2007) 316, 570-4.

2006

1

 T. Fernandez-Alfonso, R. Kwan & T. A. Ryan. Synaptic vesicles interchange their proteins with a large surface reservoir during recycling. Neuron (2006) 51,179-86.

2

 P.P. Atluri & T. A. Ryan. The kinetics of synaptic vesicle reacidification at hippocampal nerve terminals. J. Neurosci 26, 2313-2320 (2006)

3

F. E. Schweizer & T. A. Ryan. The synaptic vesicle: cycle of exocytosis and endocytosis. Current Opionion in Neurobiol. (2006) 16, 298-304.

4

 T. Fernandez-Alfonso & T. A. Ryan. The efficiency of synaptic vesicle recycling in CNS synapses Trends in Cell Biology (2006)16,413-20.

5

 T. A. Ryan. A presynaptic to-do list for coupling exocytosis and endocytosis. Current Opinion in Cell Biology (2006) 18, 416-21
2005

1

 D.L. Fortin, V.M. Nemani, S. M. Voglmaier, M.D. Anthony, T. A. Ryan & R.H. Edwards. Neural activity controls the synaptic accumulation of alpha-synuclein. J. Neurosci. 25, 10913-10921 (2005).

2

H. Hemmings, R. Westphalen, W. Yang & T. A. Ryan.The general anesthetic isoflurane depresses synaptic vesicle exocytosis Mol. Pharm. 67, 1591-1599 (2005).

3

 H. S. Moskowitz, C. T. Yokoyama & T. A. Ryan. Highly cooperative control of endocytosis by clathrin  Mo. Biol. Cell  16 , 1769-1776 (2005).

4

 S. J. Mitchell & T. A. Ryan. Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin 1-A in hippocampal neurons  Neuropharmacology 48, 372-380 (2005).
2004

1

 K. Nicholson-Tomishima & T. A. Ryan. Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I. Proc. Nat. Acad. Sci. (USA) 101, 16648-16652 (2004).

2

 G. Di Paolo, H. S. Moskowitz, K. Gibson, M. R. Wenk. S. Voronov, M. Obayahsi, R. Flavell, R. M. Fitzsimonds, T. A. Ryan & P. De Camilli. Impaired PI(4,5)P2 syntesisi in nerve terminals produces synaptic vesicle trafficking defects. Nature 431, 425-422 (2004)

3

 S. J. Mitchell & T. A. Ryan. Syntaxin-1A is excluded from recycling synaptic vesicles at nerve terminals. J. Neurosci. 24, 4884-4888 (2004).

4

T. Fernandez & T. A. Ryan. The kinetics of synaptic vesicle pool depletion at CNS nerve terminals. Neuron 41, 943-953(2004).
2003

1

 T. A. Ryan. Fluorescent Proteins with ties that bind. Nat. Biotech. 21, 1447-1448 (2003).

2

 H. S. Moskowitz, J. Heuser, T.E. McGraw & T.A. Ryan. Targetted chemical disruption of clathrin function in living cells. Mol. Biol. Cell 14, 4437-4447 (2003).

3

 P. Chi, P. Greengard & T. A. Ryan. Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies. Neuron 38, 69-78 (2003).

4

 T. A. Ryan.Kiss-and-run, fuse-pinch-and-linger, fuse-and-collapse: the life and times of a neurosecretory granule. Proc. Natl. Acad. Sci. 100 , 2171-2173 (2003)

5

 S. Sankaranarayanan, P. P. Atluri & T. A. Ryan. Actin serves a molecular scaffolding, not a propulsive role in presynaptic function. Nature Neurosci. (2003) 6, 127-135.
2002

1

 Z. Yan, P. Chi, J. A. Bibb, T. A. Ryan and P. Greengard. Roscovotine: a novel regulator of P/Q type channels and neurotransmitter release in central neurons. J. Physiol. 540, 761-770 (2002).

2

 J. Feng, P. Chi, T. A. Blanpied, Y. Xu, A. M. Magarinos, A. Ferreira, R. H. Takahashi, H. Kao, B. S. McEwen, T. A. Ryan, G. J. Augustine, and P. Greengard. Regulation of Neurotransmitter Release by Synapsin III. J. Neurosci. 22,4372-4380(2002).

3

 G. Di Paolo, S. Sankaranarayanan, M. R. Wenk, L. Daniell, E. Perucco, B. J. Caldarone, R. Flavell, M. R. Picciotto, T. A. Ryan, O. Cremona and P. De Camilli. Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron(2002) 33, 789–804 .
2001

1

 T. A. Ryan (2001) NCAM and vesicle cycling: the importance of good glue in the long run. Neuron 32, 659-671.

2

 P. Chi, P. Greengard & T. A. Ryan. (2001) Synapsin dispersion and reclustering during synaptic activity. Nature Neurosc. 4, 1187-1193.

3

 T. A. Ryan. Presynaptic Imaging Techniques. Current Opinions in Neurobiol. (2001) 11, 544-549.

4

 N. Harata, T. A. Ryan,S. J Smith, J. Buchanan & R. W. Tsien. Visualizing endocytosed synaptic vesicles in hippocampal neurons. P.N.A.S  98, 12748-12753 (2001)

5

 S. Sankaranarayanan & T. A. Ryan. Calcium accelerates endocytosis of vSNAREs at hippocampal synapses. Nature Neurosc. (2001) 4, 129-136.
2000

1

 S. Sankaranarayanan, D. De Angelis, J. E. Rothman and T. A. Ryan.The use of pHluorins for optical measurements of presynaptic activity (2000). Biophys. J. 79, 2199-2208.

2

 T. A. Ryan and H. Reuter. Measurements of vesicle recycling in central neurons (2000). N.I.P.S. in press.

3

 S. Sankaranarayanan and T.A. Ryan. Real time measurements of vSNARE recycling in CNS synapses (2000). Nature Cell Biol. 2,197-204.
1999
T. A. Ryan.Inhibitors of myosin light chain kinase block vesicle pool mobilization during action potential firing (1999). J. Neurosci. 19, 1317-1323.
1998
T. A. Ryan.Probing a complex question: when are SNARE proteins ensnared? (1998). Nature Neurosci., 1, 175-177.