Vesicle Trafficking
Synaptic Proteins Positions Open Useful Links Recent Publications Vesicle Trafficking People

groups at WMC


Vesicle trafficking is a common locus of the origin or manifestation of many human pathologies. Although nerve terminals obviously rely heavily on the careful orchestration of vesicle trafficking steps to sustain and modulate neurotransmission, all cells must have correct targetting and delivery of specific proteins to the cell surface or internal organelles.


The following is a list of either known or suspected diseases of vesicular traffic. Click on the disease to see the link (or potential link) to vesicle trafficking.

                                                                            Vesicle Trafficking Diseases

Mad Cow Disease         Atherosclerosis        Type II Diabetes    Alzheimer's Disease

Cystic Fibrosis             Griscelli Disease       Retinitis Pigmentosa     Choroideremia

Polycystic Kidney Disease                            Hermansky-Pudlack Syndrome

Chediak-Higashi Syndrome                          Williams Syndrome

Hyperkinesis                                               Liddle's Syndrome

X-linked mental retardation                           Usher's Syndrome

Mucolipidosis                                             Coagulation factor V an VII deficiency

Oculocerebrorenal Syndrome