Pharmacokinetics Simulator

Dose Number

New Peak (mcg/ml) =

New Trough (mcg/ml) =

Medical Calculators

Pharmacokinetics Simulator

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The model on which this calculator has not yet been clinically validated. Please provide the author with clinical feedback.

Calculate the volume of distribution and half life based on two plasma levels separated by a time interval. Then estimate the expected peaks and troughs on a new dosing regimen. For instructions, click on the button below.

Warning: These calculations are based on a number of assumptions that may not apply to particular clinical scenarios. The author makes no claim that the drug dosing will achieve the predicted levels. Use with extreme caution.

Weight (kg)			Medication
High Peak	Low Peak	High Trough	Low Trough	Draw Delay	Level Error	Time Error
					±	±

Dose (mg/dose)			Indexed Dose (mg/kg/dose)
Dosing Interval (hrs)			Peak-Trough Interval (hrs)
Peak (mcg/ml)			Trough (mcg/ml)


V_d(L/kg) (range) =			( - )
t_½ (hrs) (range) =			( - )
k_elim (hr^-1) (range) =			( - )

New Dose(mg)			New Indexed Dose (mg/kg)
New Dosing Interval (hr)			Peak-Trough Interval (hrs)